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Colossal Biosciences builds an AI tool to guess the dodo's missing genes

How a de-extinction company plans to work around having just one dodo genome.

Colossal Biosciences announced GenoMorph, an AI platform that combines 3D skull measurements, comparative genomics and developmental data to predict which genes could be edited when ancient DNA is scarce. The company is using it for its dodo project, where it has one genome to work with versus about 100 for the woolly mammoth. CEO Ben Lamm said the model was trained on developmental data from chickens, quail, ducks and pigeons and skull data from more than 70 bird species, and took more than a year to build.

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